Trillium Meditec

Developing and commercializing novel products utilizing hydrogel technologies to treat conditions with currently inadequate therapies

Summary

About Us

Here are some interesting points that set Trillium Meditec apart.

Funding

Looking for raising Series A to finance manufacturing, regulatory requirements for veterinary product and continued development of pipeline programs

PolyZen™

PolyZen™ injectable hydrogel technology was licensed from McMaster University on a world-wide exclusive basis for the skeletal & peripheral nervous system

Development

Currently developing treatment for OA knee pain in animals (VetZen™), humans (FlexZen™) & a 2-stage treatment approach for spinal cord injury

Founded

Invicta Biosciences was founded in 2009 with a focus on developing joint viscosupplementation products to treat knee pain associated with osteoarthritis (OA)

Our Offering - PolyZen™

An injectable hydrogel technology for the immediate management of the joint pain associated with osteoarthritis & future applications in spinal cord injury treatment, and other regenerative medicine applications

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Top 10 most costly disease to treat with an overall economic burden estimated to be t $136.8B US annually

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Case Solved

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Psychologist

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Award Won

Meet Our team

Strong Leadership Team

Nima Khadem Mohtaram, PhD | CEO & Co-founder

Nima is a Co-founder and CEO at Trillium Meditec, where he is bringing his solid skills in commercialization of Biomaterials . He is a seasoned leader served as President of Canadian Biomaterials Society and currently is teaching at University of Waterloo. Nima is a serial entrepreneur and has over 18 years of experience in developing and leading numerous projects.

Ali Riazi, PhD | Director & Co-founder

Dr. Riazi was the co-founder of Trillium Meditec (now known as Invicta Biosciences). Dr. Riazi is a scientist – entrepreneur with over 15 years of experience in the biotechnology industry at various scientific, management, and C-level positions. He possesses extensive experience in drug discovery and development, stem cell engineering, and biomolecules manufacturing and bioprocessing. He received his Ph.D. in Genetics and Molecular Biology from the University of Alberta.

Jonathan Dorogin, MASc | VP of Scientific Affairs

Jonathan Dorogin is a co-inventor of the PolyZen™ polymer family, which was developed during his time at McMaster University. He holds a Master’s in Biomedical Engineering from McMaster University and a Bachelor’s in Nanotechnology Engineering from the University of Waterloo. Jonathan is a highly skilled scientist with a background in smart materials for controlled drug delivery and tissue engineering, and a keen focus on translational science.

Todd Hoare, PhD | Scientific Advisor

Dr. Todd Hoare is the Canada Research Chair in Engineered Smart Materials and a Professor in the Department of Chemical Engineering at McMaster University. Dr. Hoare’s work on “smart” environmentally-responsive hydrogels, in situ-gelling/printable hydrogel materials, and nanoscale drug delivery vehicles has been profiled by Popular Science, Maclean’s, and BBC for its potential in solving clinical challenges through innovative materials design. He has published >100 papers and holds 7 patents which have led to four license agreements and one spin-off company. 

FAQ

All things PolyZen™

Find out more about PolyZen™ and its uses.

Degradation of cartilage and synovial fluid in the joints that prevents friction between the bones leading to constant pain & limited joint movement. Over 242M people are currently living with symptomatic and activity-limiting osteoarthritis (OA).

Current treatment options are inadequate:

  • Pain medication – only provides temporary pain management
  • Orthotics/Knee braces – discomfort & mixed results
  • Total joint replacement – invasive, costly and an end of the line necessity
  • Viscosupplementation (Intra-articular injections) – effective but degrades quickly

PolyZen™ is a zwitterionic in situ gelling hydrogel.

  • The zwitterionic component provides excellent antifouling properties that lead to high lubrication that mimics native and healthy synovial fluid
  • The in-situ gelling mechanism allows us to tailor physiochemical properties such as degradation rate and compressive strength
  • This combination of properties allows for both lubrication and mechanical support that is otherwise unavailable in a single package

Synovial Fluid

PolyZen™ exhibits the same fluid properties as healthy and natural synovial fluid & provides lubrication even under severe OA simulations.

Tunable viscosity to match synovial fluid viscosity ranges

Significantly better lubrication than leading hyaluronic acid-based viscosupplements

Cartilage

The elasticity of PolyZen™ hydrogels can be customized to levels closer to the human cartilage compared to the HA-based hydrogels

 

Contact Us

Contact Info
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